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Invitrogen™ PDGFRB (CD140b) Biosimilar Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
$459.00 - $1159.00
Specifications
Antigen | PDGFRB (CD140b) Biosimilar |
---|---|
Concentration | 1 mg/mL |
Content And Storage | -20°C, Avoid Freeze/Thaw Cycles |
Applications | ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance |
Classification | Recombinant Monoclonal |
Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term IMC-2C5.
PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB (CD140b) to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.Specifications
PDGFRB (CD140b) Biosimilar | |
-20°C, Avoid Freeze/Thaw Cycles | |
Recombinant Monoclonal | |
Lyophilized | |
IgG1 | |
Human | |
Primary | |
Protein A |
1 mg/mL | |
ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
Unconjugated | |
Human | |
RUO | |
25 mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
Antibody |
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