PDGFRB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 134491AP150UL

Catalog No. 50-172-8753

Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Specifications

• Antigen: PDGFRB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDGFRB
• Gene Alias: CD140B, JTK12, PDGF R beta, PDGF receptor beta, PDGFR, PDGFR1, PDGFRB, PDGFRbeta, PDGFR-beta
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18596, 24629, 5159
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05622, P09619, Q05030
• Gene Symbols: PDGFRB
• Immunogen: PDGFRB Fusion Protein Ag4285
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG