Invitrogen™ PDGFRL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565741

Catalog No. PIPA565741

Description

Immunogen sequence: RGFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTV Highest antigen sequence identity to the following orthologs - mouse 93%, rat 94%.

PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Specifications

• Antigen: PDGFRL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDGFRL
• Gene Alias: 1110039P19Rik; AV013190; PDGF receptor beta-like tumor suppressor; PDGFRL; PDGFR-like protein; PDGRL; platelet derived growth factor receptor like; platelet-derived growth factor receptor-like; platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor; PRLTS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5157
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15198
• Gene Symbols: PDGFRL
• Immunogen: Recombinant Human PDGFRL. Recombinant protein control fragment (Product #RP-106417).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov