Invitrogen™ PDHB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593303

Catalog No. PIPA593303

Description

Immunogen sequence: MAAVSGLVRR PLREVSGLLK RRFHWTAPAA LQVTVRDAIN QGMDEELERD EKVFLLGEEV AQYDGAYKVS RGLWKKYGDK RIIDTPISEM GFAGIAVGAA MAGLRPICEF MTFNFSMQAI DQVINSAAKT YYMSGGLQPV PIVFRGPNGA SAGVAAQHSQ CFAAWYGHCP GLKVVSPWNS EDAKGLIKSA IRDNNPVVVL ENELMYGVPF EFPPEAQSKD FLIPIGKAKI ERQGTHITVV SHSRPVGHCL EAAAVLSKEG VECEVINMRT IRPMDMETIE ASVMKTNHLV TVEGGWPQFG; Positive Samples: HL-60, HeLa, Jurkat, U-937, Mouse skeletal muscle, Rat heart; Cellular Location: Mitochondrion matrix.

PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also named as PHE1B. The enzyme, which is found in mitochondria, is one of the component enzymes of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of an oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO(2). Defects in PDHB are the cause of pyruvate dehydrogenase E1-beta deficiency (PDHBD).

Specifications

• Antigen: PDHB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDHB
• Gene Alias: 2610103L06Rik; AL024199; C81408; PDHB; PDHBD; PDHE1-B; PHE1B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289950, 5162, 68263
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11177, P49432, Q9D051
• Gene Symbols: PDHB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PDHB (NP_0009162).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG