Invitrogen™ PDIA6 Polyclonal Antibody

Catalog No.	Quantity
PIPA531834	100 μL

Catalog No. PIPA531834 Supplier Invitrogen™ Supplier No. PA531834

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Raji. Predicted reactivity: Mouse (94%), Rat (94%), Pig (94%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

P5 is a novel protein that was originally identified in humans. Functionally, P5 has been shown to have peptide binding ability and chaperone activity specific to certain proteins. P5 shares several structural similarities to PDI, an important protein of the ER. The deduced amino acid sequence of P5 shows that it contains the ER retention signal KDEL. P5 also contains two CXXC-like motifs, a motif responsible for oxidoreductase activity. These two CXXC motifs are found on the N- and C-terminus of the protein, one at each end. Studies suggest that the N-terminal CXXC motif is more important than the second for isomerase activity. Contrary to most of the PDI-like proteins, P5 is not stress-inducible.

Specifications

• Antigen: PDIA6
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene: PDIA6
• Gene Accession No.: Q15084, Q63081, Q922R8
• Gene Alias: 1700015E05Rik; AL023058; C77895; CaBP1; CaBP5; Calcium-binding protein 1; endoplasmic reticulum protein 5; ER protein 5; ERP5; P5; PDIA6; pdi-p5; protein disulfide isomerase A6; protein disulfide isomerase associated 6; protein disulfide isomerase family A member 6; protein disulfide isomerase family A, member 6; protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain containing 7 (protein disulfide isomerase); thioredoxin domain-containing protein 7; TXNDC7
• Gene Symbols: PDIA6
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PDIA6. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10130, 286906, 71853
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG