Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ PDLIM1 Recombinant Rabbit Monoclonal Antibody (JE55-21)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA536211

Catalog No. PIMA536211


Only null left
Add to Cart

Description

Description

PDLIM1 Recombinant Monoclonal Antibody for Western Blot, IHC (P), Flow

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PDLIM1
Recombinant Monoclonal
1 mg/mL
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
O00151, O70400, P52944
Pdlim1
Recombinant protein within Human PDLIM1 aa 181-285.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
JE55-21
Unconjugated
Pdlim1
carboxyl terminal LIM domain protein 1; Clim1; Clp36; CLP-36; C-terminal LIM domain protein 1; elfin; enigma; epididymis secretory protein Li 112; hCLIM1; HEL-S-112; LIM domain protein CLP-36; LIM protein; mClim1; Pdlim1; PDZ and LIM domain 1; PDZ and LIM domain 1 (elfin); PDZ and LIM domain protein 1
Rabbit
Protein A
RUO
54132, 54133, 9124
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.