Invitrogen™ PDLIM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528631

Catalog No. PIPA528631

Description

Recommended positive controls: PDLIM3 tansfected 293T cell. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PDLIM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDLIM3
• Gene Alias: actinin alpha 2 associated LIM protein; actinin-associated LIM protein; Actn2lp; AI463105; ALP; alpha-actinin-2-associated LIM protein; enigma homolog; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; SK-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27295
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.75 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q53GG5
• Gene Symbols: PDLIM3
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALP. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG