Invitrogen™ PDLIM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552099

Catalog No. PIPA552099

Description

Immunogen sequence: WGFRLSGGID FNQPLVITRI TPGSKAAAAN LCPGDVILAI DGFGTESMTH ADAQDRIKAA AHQLCLKIDR GETHLWSPQV SEDGKA Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PDLIM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDLIM3
• Gene Alias: actinin alpha 2 associated LIM protein; actinin-associated LIM protein; Actn2lp; AI463105; ALP; alpha-actinin-2-associated LIM protein; enigma homolog; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; SK-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27295
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q53GG5
• Gene Symbols: PDLIM3
• Immunogen: Recombinant protein corresponding to Human PDLIM3. Recombinant protein control fragment (Product #RP-88638).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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