Invitrogen™ PDLIM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592915

Catalog No. PIPA592915

Description

Immunogen sequence: KAAAHQLCLK IDRGETHLWS PQVSEDGKAH PFKINLESEP QEFKPIGTAH NRRAQPFVAA ANIDDKRQVV SASYNSPIGL YSTSNIQDAL HGQLRGLIPS SPQNEPTASV PPESDVYRML HDNRNEPTQP RQSGSFRVLQ GMVDDGSDDR PAGTRSVRAP V; Positive Samples: Mouse lung; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere.

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PDLIM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDLIM3
• Gene Alias: actinin alpha 2 associated LIM protein; actinin-associated LIM protein; Actn2lp; AI463105; ALP; alpha-actinin-2-associated LIM protein; enigma homolog; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; SK-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53318
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O70209
• Gene Symbols: PDLIM3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_0011075791).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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