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Invitrogen™ PDLIM3 Polyclonal Antibody
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Catalog No. PIPA592915
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100 μL
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PIPA592915 100 μL
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Catalog No. PIPA592915 Supplier Invitrogen™ Supplier No. PA592915
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KAAAHQLCLK IDRGETHLWS PQVSEDGKAH PFKINLESEP QEFKPIGTAH NRRAQPFVAA ANIDDKRQVV SASYNSPIGL YSTSNIQDAL HGQLRGLIPS SPQNEPTASV PPESDVYRML HDNRNEPTQP RQSGSFRVLQ GMVDDGSDDR PAGTRSVRAP V; Positive Samples: Mouse lung; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere.

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDLIM3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PDLIM3
Gene Accession No. O70209
Gene Alias actinin alpha 2 associated LIM protein; actinin-associated LIM protein; Actn2lp; AI463105; ALP; alpha-actinin-2-associated LIM protein; enigma homolog; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; SK-2
Gene Symbols PDLIM3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_0011075791).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53318
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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