Invitrogen™ PDP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120280

Catalog No. PIPA5120280

Description

Positive test controls include: 293T, U-87MG, DU145, 5637, mouse brain, mouse skeletal muscle, mouse heart, rat skeletal muscle, rat heart. The target is usually found in the following locations: Mitochondrion matrix. Immunogen sequence: ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID VKEALINAFK RLDNDISLEA QVGDPNSFL.

PDP1 is a Pyruvate dehydrogenase and helps catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.

Specifications

• Antigen: PDP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDP1
• Gene Alias: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; Gm1024; MGC119646; PDH; PDP; PDP 1; PDP1; PDPC; PDPC 1; PPM2A; Ppm2c; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 1; pyruvate dehyrogenase phosphatase catalytic subunit 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 381511, 54704, 54705
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 3.41 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O88483, Q3UV70, Q9P0J1
• Gene Symbols: PDP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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