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Invitrogen™ PDX1 Monoclonal Antibody (5A5)
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Catalog No. PIMA517148
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100 μg
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Catalog No. Quantity
PIMA517148 100 μg
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Catalog No. PIMA517148 Supplier Invitrogen™ Supplier No. MA517148
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Mouse Monoclonal Antibody

MA5-17148 targets PDX1 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17148 immunogen is purified recombinant fragment of human PDX1 expressed in E. Coli. MA5-17148 detects PDX1 which has a predicted molecular weight of approximately 30.8kDa.

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDX1
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 5A5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene PDX1
Gene Accession No. P52945
Gene Alias DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
Gene Symbols PDX1
Host Species Mouse
Immunogen Purified recombinant fragment of human PDX1 expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3651
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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