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Pdx1 Mouse anti-Human, Clone: OTI2A12, liquid, TrueMAB™
SDP

Catalog No. 501671348
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50-167-1348 30 μL
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Catalog No. 50-167-1348 Supplier OriGene Supplier No. TA500038S
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Description

Mouse Monoclonal Antibody

pdx-1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.

Specifications

Antigen Pdx1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2A12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene PDX1
Gene Accession No. P52945
Gene Alias GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
Gene Symbols PDX1
Host Species Mouse
Immunogen Full length human recombit protein of human PDX1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 30 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3651
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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