PDX1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 61289

Catalog No. 50-199-3305

Description

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Specifications

• Antigen: PDX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDX1
• Gene Alias: BOS_12504; DLDBP; E3BP; Glucose-sensitive factor; GSF; homeobox protein PDX-1; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; Insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; Islet/duodenum homeobox-1; IUF1; IUF-1; LOW QUALITY PROTEIN: pancreas/duodenum homeobox protein 1; Mody4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic and duodenum homeobox 1; pancreatic duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; PDX-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; Somatostatin-transactivating factor 1; STF1; STF-1; zgc:100874
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3651
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: Lot-Specific
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Accession No.: P52945
• Gene Symbols: PDX1
• Immunogen: This PDX1 antibody was raised against a peptide within the N-terminal region of human PDX1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG