Invitrogen™ PDZD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521886

Catalog No. PIPA521886

Description

Recommended positive controls: A549. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Specifications

• Antigen: PDZD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDZD2
• Gene Alias: 4930537L06Rik; A930022H17Rik; activated in prostate cancer protein; AIPC; Gm82; KIAA0300; mKIAA0300; PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZD2; PDZK3; Pin1; Plakophilin-related armadillo repeat protein-interacting PDZ protein; plakophilin-related armadillo repeat protein-interactive PDZ protein; Processed PDZ domain-containing protein 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23037
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15018
• Gene Symbols: PDZD2
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 44 of PDZK3 (Uniprot ID#O15018).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG