Invitrogen™ PDZD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104478

Catalog No. PIPA5104478

Description

Antibody detects endogenous levels of total PDZD2.

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Specifications

• Antigen: PDZD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDZD2
• Gene Alias: 4930537L06Rik; A930022H17Rik; activated in prostate cancer protein; AIPC; Gm82; KIAA0300; mKIAA0300; PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZD2; PDZK3; Pin1; Plakophilin-related armadillo repeat protein-interacting PDZ protein; plakophilin-related armadillo repeat protein-interactive PDZ protein; Processed PDZ domain-containing protein 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23037, 65034, 68070
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O15018, Q9QZR8
• Gene Symbols: PDZD2
• Immunogen: A synthesized peptide derived from human PDZD2(Accession O15018), corresponding to amino acid residues E67-G117.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov