PDZK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-6362	150 μL

Catalog No. 50-172-6362 Supplier Proteintech Group Inc Supplier No. 105072AP150UL

Description

Rabbit Polyclonal Antibody

PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. It may also play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. PDZK1 functions to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism and may be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Specifications

• Antigen: PDZK1
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.22 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PDZK1
• Gene Accession No.: Q5T2W1, Q9JIL4, Q9JJ40
• Gene Alias: CAP70, CLAMP, NaPi Cap1, NHERF 3, NHERF3, PDZ domain containing 1, PDZD1, PDZK1
• Gene Symbols: Pdzk1
• Host Species: Rabbit
• Immunogen: PDZK1 Fusion Protein Ag0787
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5174, 59020, 65144
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG