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Invitrogen™ PEG (methoxy group) Recombinant Rabbit Monoclonal Antibody (RM105)
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Catalog No. PIMA524693
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100 μg
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PIMA524693 100 μg
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Catalog No. PIMA524693 Supplier Invitrogen™ Supplier No. MA524693
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody reacts to the methoxy group of Polyethylene glycol (PEG). It is specific for methoxypoly(ethylene glycol). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

PEG recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEG (methoxy group)
Applications ELISA, Immunohistochemistry, Western Blot
Classification Recombinant Monoclonal
Clone RM105
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Alias Poly Ethylene Glycol; Polyethylene Glycol
Host Species Rabbit
Immunogen KLH-PEG with terminal methoxy group.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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