Invitrogen™ PEG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555282

Catalog No. PIPA555282

Description

Immunogen sequence: SSNVREYQKA RAKKKYIEHR SNETSVIHSL PFGEQTFRPR GMLYECQECG ECFAHSSDLT EHQKIHDREK PSGSRNYEWS VIRSLAPTDP QTSYAQEQYA KEQARNKCKD FRQFFATSED LNTNQKIYDQ Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 69%.

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: PEG3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEG3
• Gene Alias: AL022617; ASF-1; End4; Gcap4; granule cell antiserum positive 4; KIAA0287; Kruppel-type zinc finger protein; mKIAA0287; paternally expressed 3; paternally expressed gene 3; paternally-expressed gene 3 protein; PEG3; Pw1; Zfp102; zinc finger and SCAN domain-containing protein 24; ZKSCAN22; ZNF904; ZSCAN24
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5178
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9GZU2
• Gene Symbols: PEG3
• Immunogen: Recombinant protein corresponding to Human PEG3. Recombinant protein control fragment (Product #RP-89445).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG