Invitrogen™ PEG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599683

Catalog No. PIPA599683

Description

Antibody detects endogenous levels of total PEG3.

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: PEG3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEG3
• Gene Alias: AL022617; ASF-1; End4; Gcap4; granule cell antiserum positive 4; KIAA0287; Kruppel-type zinc finger protein; mKIAA0287; paternally expressed 3; paternally expressed gene 3; paternally-expressed gene 3 protein; PEG3; Pw1; Zfp102; zinc finger and SCAN domain-containing protein 24; ZKSCAN22; ZNF904; ZSCAN24
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103691034, 18616, 5178
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3URU2, Q9GZU2
• Gene Symbols: PEG3
• Immunogen: A synthesized peptide derived from human PEG3(Accession Q9GZU2), corresponding to amino acid residues G1427-G1477.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG