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Invitrogen™ PEG3 Polyclonal Antibody
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Catalog No. PIPA5116550
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100 μL
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PIPA5116550 100 μL
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Catalog No. PIPA5116550 Supplier Invitrogen™ Supplier No. PA5116550
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Description

Rabbit Polyclonal Antibody

Positive Samples: HepG2 Immunogen sequence: LSLPVVAKTS FEMDREDDRD SRAYESRSQD AESYQNVVDL AEDRKPHNTI QDNMENYRKL LSLVQLAEDD GHSHMTQGHS SRSKRSAYPS TSRGLKTMPE AKKSTHRRGI CEDESSHGVI MEKFIKDVSR SSKSGRARES SDRSQRFPRM SDDNWKDISL NKRESVIQQR VYEGNAFRGG FRFNSTLVSR KRVLERKRRY HFDTDG.

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEG3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PEG3
Gene Accession No. Q3URU2, Q9GZU2
Gene Alias AL022617; ASF-1; End4; Gcap4; granule cell antiserum positive 4; KIAA0287; Kruppel-type zinc finger protein; mKIAA0287; paternally expressed 3; paternally expressed gene 3; paternally-expressed gene 3 protein; PEG3; Pw1; Zfp102; zinc finger and SCAN domain-containing protein 24; ZKSCAN22; ZNF904; ZSCAN24
Gene Symbols PEG3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 195-400 of human PEG3 (NP_0062011).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103691034, 18616, 5178
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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