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Invitrogen™ Pellino 2 Polyclonal Antibody
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Catalog No. PIPA530701
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100 μL
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Catalog No. Quantity
PIPA530701 100 μL
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Catalog No. PIPA530701 Supplier Invitrogen™ Supplier No. PA530701
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HepG2, HCT116. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (80%), Xenopus laevis (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pellino 2
Applications Western Blot
Classification Polyclonal
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Peli2
Gene Accession No. Q9HAT8
Gene Alias AW047589; BB129927; E3 ubiquitin-protein ligase pellino homolog 2; Peli2; pellino 2; pellino E3 ubiquitin protein ligase family member 2; pellino homolog 2; pellino-2; protein pellino homolog 2; RGD1565884; RING-type E3 ubiquitin transferase pellino homolog 2
Gene Symbols Peli2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Pellino 2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57161
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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