Invitrogen™ Pellino 2 Polyclonal Antibody

Catalog No.	Quantity
PIPA562754	100 μL

Catalog No. PIPA562754 Supplier Invitrogen™ Supplier No. PA562754

Description

Rabbit Polyclonal Antibody

Immunogen sequence: NRKEVVEEKQ PWAYLSCGHV HGYHN Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. [UniProt].

Specifications

• Antigen: Pellino 2
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Peli2
• Gene Accession No.: Q9HAT8
• Gene Alias: AW047589; BB129927; E3 ubiquitin-protein ligase pellino homolog 2; Peli2; pellino 2; pellino E3 ubiquitin protein ligase family member 2; pellino homolog 2; pellino-2; protein pellino homolog 2; RGD1565884; RING-type E3 ubiquitin transferase pellino homolog 2
• Gene Symbols: Peli2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human Pellino 2. Recombinant protein control fragment (Product #RP-100026).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57161
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG