Pembrolizumab Mouse, Biotin, Clone: 10E12C6, GenScript™

Mouse Monoclonal Antibody

Supplier:  Genscript Corporation A0184540

Catalog No. 50-212-0616

Description

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. GenScript Anti-Pembrolizumab Antibody (10E12C6)[BIOTIN], mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Pembrolizumab.

Pembrolizumab Monoclonal antibody specifically detects Pembrolizumab in Chemical samples. It is validated for Blocking assay, ELISA

Specifications

• Antigen: Pembrolizumab
• Classification: Monoclonal
• Conjugate: Biotin
• Gene Alias: Keytruda
• Immunogen: Pembrolizumab
• Quantity: 40 μg
• Primary or Secondary: Primary
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Blocking Assay, ELISA
• Clone: 10E12C6
• Formulation: PBS with BSA and 0.02% sodium azide; pH 7.4
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Content And Storage: -20°C or -80°C if preferred
• Form: Lyophilized
• Target Molecule: Chemical