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Pembrolizumab Mouse, Biotin, Clone: 10E12C6, GenScript™

Catalog No. 502120616
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50-212-0616 40 μg
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Catalog No. 50-212-0616 Supplier Genscript Corporation Supplier No. A0184540
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Description

Mouse Monoclonal Antibody

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. GenScript Anti-Pembrolizumab Antibody (10E12C6)[BIOTIN], mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Pembrolizumab.

Pembrolizumab Monoclonal antibody specifically detects Pembrolizumab in Chemical samples. It is validated for Blocking assay, ELISA

Specifications

Antigen Pembrolizumab
Applications Blocking Assay, ELISA
Classification Monoclonal
Clone 10E12C6
Conjugate Biotin
Formulation PBS with BSA and 0.02% sodium azide; pH 7.4
Gene Alias Keytruda
Host Species Mouse
Immunogen Pembrolizumab
Purification Method Protein A
Quantity 40 μg
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Lyophilized
Isotype IgG1 κ
Target Molecule Chemical
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