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Invitrogen™ PEN2 Recombinant Rabbit Monoclonal Antibody (JE41-28)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA534830
Description
Positive Control: Mouse spleen tissue, rat cerebellum tissue, human tonsil tissue, human lung cancer tissue, human kidney tissue, mouse testis tissue, A549, SH-SY-5Y.
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Specifications
PEN2 | |
Recombinant Monoclonal | |
1 mg/mL | |
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
Q9NZ42 | |
PSENEN | |
Recombinant protein within Human PEN2 aa 1-101. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
JE41-28 | |
Unconjugated | |
PSENEN | |
1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037 | |
Rabbit | |
Protein A | |
RUO | |
55851 | |
-20°C, Avoid Freeze/Thaw Cycles, store in dark | |
Liquid |
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