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Pentraxin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501729013 Shop All Proteintech Group Inc Products
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50-172-9013 150 μL
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Catalog No. 50-172-9013 Supplier Proteintech Group Inc Supplier No. 137971AP150UL
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Description

Rabbit Polyclonal Antibody

Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of "long pentraxins", which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.

Specifications

Antigen Pentraxin 3
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PTX3
Gene Accession No. P26022, P48759
Gene Alias Pentaxin related protein PTX3, Pentraxin 3, Pentraxin related protein PTX3, PTX3, TNF alpha induced protein 5, TNFAIP5, TSG 14, TSG14
Gene Symbols PTX3
Host Species Rabbit
Immunogen Pentraxin 3 Fusion Protein Ag4624
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19288, 5806, 689388
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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