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Invitrogen™ PEO1 Polyclonal Antibody
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Catalog No. PIPA551715
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PIPA551715 100 μL
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Catalog No. PIPA551715 Supplier Invitrogen™ Supplier No. PA551715
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Rabbit Polyclonal Antibody

Immunogen sequence: SKAPEFEDSE EVRRIWNRAI PLWELPDQEE VQLADTMFGL TKVTDDTLKR FSVRYLRPAR SLVFPWFSPG GSGLRGLKLL EAKCQGDGVS YEETTIPRPS AYHNLFGLPL ISRRDAEVVL TSRELDSLAL NQSTG Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 78%.

Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEO1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TWNK
Gene Accession No. Q96RR1
Gene Alias ataxin 8; Ataxin8; ATXN 8; ATXN8; C10 orf2; C10orf 2; C10orf2; C18H10orf2; C1H10orf2; C26H10orf2; C28H10orf2; chromosome 10 open reading frame 2; D19Ertd626e; fi04d09; FLJ21832; IOSCA; mitochondrial twinkle protein; MTDPS7; PEO; PEO 1; peo1; PEOA3; PRLTS5; progressive external ophthalmoplegia 1; progressive external ophthalmoplegia 1 (human); progressive external ophthalmoplegia 1 homolog; progressive external ophthalmoplegia 1 protein; Progressive external ophthalmoplegia 1 protein homolog; SANDO; SCA 8; SCA8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; twinkle; Twinkle mtDNA helicase; twinkle protein, mitochondrial; twinkle protein, mitochondrial-like; Twinkle protein, mitochondrial-like protein; Twinl; Twnk; wu:fi04d09
Gene Symbols TWNK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PEO1. Recombinant protein control fragment (Product #RP-102228).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56652
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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