Invitrogen™ PEO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589232

Catalog No. PIPA589232

Description

Positive Samples: Mouse kidney; Cellular Location: Mitochondrion matrix, mitochondrion nucleoid Immunogen sequence: NVLILQDRKL VTGPGKRYLQ VSKNRFDGDV GVFPLEFNKN SLTFSIPPKN KARLKKIKDD TGPVAKKPSS GKKGATTQNS EICSGQAPTP DQPDTSKRSK.

Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: PEO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TWNK
• Gene Alias: ataxin 8; Ataxin8; ATXN 8; ATXN8; C10 orf2; C10orf 2; C10orf2; C18H10orf2; C1H10orf2; C26H10orf2; C28H10orf2; chromosome 10 open reading frame 2; D19Ertd626e; fi04d09; FLJ21832; IOSCA; mitochondrial twinkle protein; MTDPS7; PEO; PEO 1; peo1; PEOA3; PRLTS5; progressive external ophthalmoplegia 1; progressive external ophthalmoplegia 1 (human); progressive external ophthalmoplegia 1 homolog; progressive external ophthalmoplegia 1 protein; Progressive external ophthalmoplegia 1 protein homolog; SANDO; SCA 8; SCA8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; twinkle; Twinkle mtDNA helicase; twinkle protein, mitochondrial; twinkle protein, mitochondrial-like; Twinkle protein, mitochondrial-like protein; Twinl; Twnk; wu:fi04d09
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226153, 56652
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8CIW5, Q96RR1
• Gene Symbols: TWNK
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 585-684 of human C10orf2 (NP_0686022).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG