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Invitrogen™ PEPCK2 Polyclonal Antibody
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Catalog No. PIPA597059
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100 μL
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PIPA597059 100 μL
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Catalog No. PIPA597059 Supplier Invitrogen™ Supplier No. PA597059
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAALYRPGLR LNWHGLSPLG WPSCRSIQTL RVLSGDLGQL PTGIRDFVEH SARLCQPEGI HICDGTEAEN TATLTLLEQQ GLIRKLPKYN NCWLARTDPK DVARVESKTV IVTPSQRDTV QLPPGGARGQ LGNWMSPADF QRAVDERFPG CMQGRTMYVL PFSMGPVGSP LSRIGVQLTD SAYVVASMRI MTRLGTPVLQ ALGDGDFVKC LHSVGQPLTG QGEPVSQWPC NPEKTLIGHV PDQREIISFG SGYGGNSLLG KKCFALRIAS RLARDEGWLA; Positive Samples: SH-SY5Y, LO2, HepG2, Mouse testis, Mouse brain, Mouse kidney, Rat brain; Cellular Location: Mitochondrion.

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEPCK2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PCK2
Gene Accession No. Q16822, Q8BH04
Gene Alias 1810010O14Rik; 9130022B02Rik; HGNC:8725; PCK2; PEP carboxykinase; PEPCK; PEPCK2; PEPCK-M; Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; phosphoenolpyruvate carboxykinase 2 (mitochondrial); phosphoenolpyruvate carboxykinase 2, mitochondrial; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase
Gene Symbols PCK2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PEPCK/PEPCK/PCK2 (NP_0045542).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361042, 5106, 74551
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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