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Invitrogen™ Pepsin A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA536559
Description
This antibody detects endogenous protein at a molecular weight of 42 kDa. Purity is >95% by SDS-PAGE.
Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Pepsin A is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. Pepsin A is inhibited by ovUS-1, a uterine serpin.
Specifications
Pepsin A | |
Polyclonal | |
Unconjugated | |
PGA3 | |
1110035E17Rik; Pepf; pepsin A; pepsin A-3; Pepsin A-4; pepsin A-5; Pepsin F; pepsinogen 3, group I (pepsinogen A); pepsinogen 4, group I (pepsinogen A); pepsinogen 5, group I; pepsinogen 5, group I (pepsinogen A); pepsinogen A3; pepsinogen A4; pepsinogen A5; pepsinogen F; pepsinogen F protein; pepsinogen-3; Pepsinogen-4; pepsinogen-5; Pg5; PGA3; PGA4; PGA5 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
5222, 58803, 60372, 643834, 643847 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
P0DJD7, P0DJD8, P0DJD9, Q9D106 | |
PGA3, PGA4, PGA5 | |
Synthetic peptide corresponding to amino acids 281-330 of human Pepsin A. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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