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Pepsinogen I Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen Pepsinogen I
Concentration 0.23 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-1514
SDP
Encompass_Preferred
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Proteintech Group Inc
173301AP150UL
150 μL
Each of 1 for $518.60
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Description

Description

This antibody can recognize PGA3 (pepsinogen 3), PGA4(pepsinogen 4), PGA5(pepsinogen 5).

PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predomit endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.
Specifications

Specifications

Pepsinogen I
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
P0DJD9, Q9D106
5222, 58803, 60372
Pepsinogen I Fusion Protein Ag11309
Primary
-20°C
PGA5
0.23 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Pepsin A, pepsinogen 5, group I (pepsinogen A), Pepsinogen I, PGA3, PGA4, PGA5
PGA5
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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