Invitrogen™ Peptide Histidine-Methionine Monoclonal Antibody (03)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ ABS0200302

Catalog No. ABA-200302

Description

ABS 020-03-02 detects PHM in human samples. ABS 020-03-02 has been successfully used in ELISA procedures. PHM cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition). NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.

Specifications

• Antigen: Peptide Histidine-Methionine
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01282
• Gene Symbols: VIP
• Immunogen: Synthetic human peptide histidine-methionine.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Immunohistochemistry
• Clone: 03
• Conjugate: Unconjugated
• Gene: VIP
• Gene Alias: Intestinal peptide PHM-27; Intestinal peptide PHV-42; MGC13587; Peptide histidine methioninamide 27; Peptide histidine valine 42; PHM27; prepro-VIP; vasoactive intestinal peptide; Vasoactive intestinal polypeptide; VIP; VIP peptides
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 7432
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov