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Invitrogen™ Peptidylarginine Deiminase Polyclonal Antibody
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Catalog No. PIPA564014
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100 μL
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PIPA564014 100 μL
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Catalog No. PIPA564014 Supplier Invitrogen™ Supplier No. PA564014
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PSACLKLFQE KKEEGYGEAA QFDGLKHQAK RSINEMLADR HLQRDNLHAQ KCIDWN Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Peptidylarginine Deiminase
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PADI1
Gene Accession No. Q9ULC6
Gene Alias HPAD10; hPAD-colony 10; PAD1; PADI1; PADI5; PDI; PDI1; PDI2; PDI3; PDI4; peptidyl arginine deiminase 1; peptidyl arginine deiminase, type I; peptidylarginine deiminase I; Protein-arginine deiminase type I; protein-arginine deiminase type-1
Gene Symbols PADI1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Peptidylarginine Deiminase. Recombinant protein control fragment (Product #RP-103444).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29943
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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