Invitrogen™ PER3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554014

Catalog No. PIPA554014

Description

Immunogen sequence: QPVHVSVSSG YGSLGSSGSQ EQLVSIASSS EASGHRVEET KAEQMTLQQV YASVNKIKNL GQQLYIESMT KSSFKPVTGT RTEPNGGGES ANGGGECKTF TSFHQTLKNN SVYTEPCEDL RNDEHSPSYQ QIN Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 66%.

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PER3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PER3
• Gene Alias: 2810049O06Rik; Cell growth-inhibiting gene 13 protein; circadian clock protein PERIOD 3; FASPS3; GIG13; hPER3; mPER3; Per3; period circadian clock 3; period circadian protein 3; period circadian protein homolog 3; period homolog 3; period3; rper3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8863
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P56645
• Gene Symbols: PER3
• Immunogen: Recombinant protein corresponding to Human PER3. Recombinant protein control fragment (Product #RP-91592).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG