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Invitrogen™ Pericentrin Polyclonal Antibody
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Catalog No. PIPA537295
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100 μL
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PIPA537295 100 μL
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Catalog No. PIPA537295 Supplier Invitrogen™ Supplier No. PA537295
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 76 kDa. Purity is >95% by SDS-PAGE.

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pericentrin
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PCNT
Gene Accession No. O95613, P48725
Gene Alias AW476095; C86676; KEN; kendrin; KIAA0402; m239Asp; m275Asp; MOPD2; PCN; Pcnt; PCNT2; PCNTB; PCTN2; Pericentrin; pericentrin (kendrin); pericentrin 2; pericentrin-2; pericentrin-250; pericentrin-360; pericentrin-380; pericentrin-B; SCKL4
Gene Symbols PCNT
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human PCNT.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18541, 309692, 5116
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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