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Perilipin 5 Rabbit anti-Human, Mouse, Porcine, Polyclonal, Proteintech
SDP

Catalog No. 501735514 Shop All Proteintech Group Inc Products
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50-173-5514 150 μL
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Catalog No. 50-173-5514 Supplier Proteintech Group Inc Supplier No. 269511AP150UL
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Description

Rabbit Polyclonal Antibody

Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.

Specifications

Antigen Perilipin 5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene PLIN5
Gene Accession No. Q00G26, Q8BVZ1
Gene Alias LSDP5, OXPAT, Perilipin 5, PLIN5
Gene Symbols PLIN5
Host Species Rabbit
Immunogen Perilipin 5 Fusion Protein Ag25272
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100142670, 440503, 66968
Target Species Human, Mouse, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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