Invitrogen™ Perlecan Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121692

Catalog No. PIPA5121692

Description

Perlecan Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

Specifications

• Antigen: Perlecan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPG2
• Gene Alias: AI852380; Basement membrane-specific heparan sulfate proteoglycan core protein; Endorepellin; endorepellin (domain V region); heparan sulfate proteoglycan 2; HSPG; Hspg2; LG3 peptide; LOC313641; Pcn; per; perlecan; perlecan (heparan sulfate proteoglycan 2); perlecan proteoglycan; PLC; PRCAN; RP11-132G19.2; SJA; SJS; SJS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100517288, 15530, 313641, 3339
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P98160, Q05793
• Gene Symbols: HSPG2
• Immunogen: Recombinant protein Heparan Sulfate Proteoglycan 2. The antigen corresponds to amino acid range 4149-4391 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig, Rat
• Product Type: Antibody
• Isotype: IgG