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Invitrogen™ Perlecan Polyclonal Antibody
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Catalog No. PIPA5140142
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100 μL
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PIPA5140142 100 μL
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Catalog No. PIPA5140142 Supplier Invitrogen™ Supplier No. PA5140142
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: RGMVFGIPDG VLELVPQRGP CPDGHFYLEH SAACLPCFCF GITSVCQSTR RFRDQIRLRF DQPDDFKGVN VTMPAQPGTP PLSSTQLQID PSL Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 88%.

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Perlecan
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HSPG2
Gene Accession No. P98160
Gene Alias AI852380; Basement membrane-specific heparan sulfate proteoglycan core protein; Endorepellin; endorepellin (domain V region); heparan sulfate proteoglycan 2; HSPG; Hspg2; LG3 peptide; LOC313641; Pcn; per; perlecan; perlecan (heparan sulfate proteoglycan 2); perlecan proteoglycan; PLC; PRCAN; RP11-132G19.2; SJA; SJS; SJS1
Gene Symbols HSPG2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HSPG2. Recombinant protein control fragment (Product #RP-109301).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3339
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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