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Invitrogen™ PERP Recombinant Rabbit Monoclonal Antibody (1O3L5)
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Catalog No. PIMA538148
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PIMA538148 100 μL
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Catalog No. PIMA538148 Supplier Invitrogen™ Supplier No. MA538148
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HepG2, BxPC-3, A-431, Mouse liver, Mouse kidney, Rat lung, Rat liver Immunogen sequence: LSFFALCGPQ MLVFLRVIGG LLALAAVFQI ISLVIYPVKY TQTFTLHANP AVTYIYNWAY GFGWAATIIL IGCAFFFCCL PNYEDDLLGN AKPRYFYTSA.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PERP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 1O3L5
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PERP
Gene Accession No. Q96FX8, Q9JK95
Gene Alias 1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW
Gene Symbols PERP
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292949, 64058, 64065
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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