Invitrogen™ PEX12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104003

Catalog No. PIPA5104003

Description

Antibody detects endogenous levels of total PEX12.

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.

Specifications

• Antigen: PEX12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEX12
• Gene Alias: AI451906; PAF3; PAF-3; PBD3A; peroxin 12; peroxin-12; peroxisomal biogenesis factor 12; peroxisome assembly factor 3; Peroxisome assembly protein 12; Pex12
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103737, 116718, 5193
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O00623, O88177, Q8VC48
• Gene Symbols: PEX12
• Immunogen: A synthesized peptide derived from human PEX12(Accession O00623), corresponding to amino acid residues G201-L251.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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