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Invitrogen™ PEX13 Polyclonal Antibody
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Catalog No. PIPA521751
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100 μL
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PIPA521751 100 μL
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Catalog No. PIPA521751 Supplier Invitrogen™ Supplier No. PA521751
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PEX13 (Peroxisomal Biogenesis Factor 13) is a gene located on chromosome 2p15 that encodes a peroxisomal membrane protein essential for the biogenesis and function of peroxisomes, which are cellular organelles involved in lipid metabolism and detoxification of reactive oxygen species. PEX13 is a component of the peroxisomal import machinery that specifically recognizes and binds to peroxisomal targeting signal 1 (PTS1) containing proteins, facilitating their import into the peroxisome matrix. Mutations in the PEX13 gene can lead to Zellweger spectrum disorders, a group of peroxisome biogenesis disorders (PBDs) characterized by defects in multiple peroxisomal metabolic pathways, leading to severe developmental issues, neurological deficits, and often early lethality. Studies of PEX13 have helped elucidate the mechanisms of peroxisomal protein import and the broader implications of peroxisomal dysfunction in human disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEX13
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene PEX13
Gene Accession No. Q92968
Gene Alias NALD; PBD11A; PBD11B; Peroxin-13; peroxisomal biogenesis factor 13; peroxisomal membrane protein PEX13; peroxisome biogenesis factor 13; Pex13; ZWS
Gene Symbols PEX13
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PEX13. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5194
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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