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Invitrogen™ PEX19 Monoclonal Antibody (GT554)
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Catalog No. PIMA517266
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100 μL
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PIMA517266 100 μL
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Catalog No. PIMA517266 Supplier Invitrogen™ Supplier No. MA517266
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Jurkat, Raji, K562, THP-1, HL-60, NCI-H929, mouse liver. Predicted reactivity: Mouse (91%), Rat (93%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEX19
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT554
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene PEX19
Gene Accession No. P40855, Q8VCI5
Gene Alias 33 kDa housekeeping protein; D1S2223E; HK33; housekeeping gene, 33kD; OK/SW-cl.22; PBD12A; peroxin-19; Peroxisomal biogenesis factor 19; peroxisomal farnesylated protein; peroxisome biogenesis factor 19; Pex19; PMP1; PMPI; PxF; PXMP1
Gene Symbols PEX19
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human PEX19. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19298, 5824
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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