Invitrogen™ PEX19 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102781

Catalog No. PIPA5102781

Description

Antibody detects endogenous levels of total PEX19.

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).

Specifications

• Antigen: PEX19
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEX19
• Gene Alias: 33 kDa housekeeping protein; D1S2223E; HK33; housekeeping gene, 33kD; OK/SW-cl.22; PBD12A; peroxin-19; Peroxisomal biogenesis factor 19; peroxisomal farnesylated protein; peroxisome biogenesis factor 19; Pex19; PMP1; PMPI; PxF; PXMP1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19298, 289233, 5824
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P40855, Q8VCI5, Q9QYU1
• Gene Symbols: PEX19
• Immunogen: A synthesized peptide derived from human PEX19(Accession P40855), corresponding to amino acid residues Y218-L268.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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