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Invitrogen™ PEX5 Polyclonal Antibody
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Catalog No. PIPA558717
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100 μL
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PIPA558717 100 μL
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Catalog No. PIPA558717 Supplier Invitrogen™ Supplier No. PA558717
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RAQAEQWAAE FIQQQGTSDA WVDQFTRPVN TSALDMEFER AKSAIESDVD FWDKLQAELE EMAKRDAEAH PWLSDYDDLT SATYDKGYQF EEEN Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEX5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pex5
Gene Accession No. P50542
Gene Alias AW212715; ESTM1; LOW QUALITY PROTEIN: peroxisomal biogenesis factor 5; PBD2A; PBD2B; peroxin 5; peroxin-5; peroxisomal biogenesis factor 5; peroxisomal C-terminal targeting signal import receptor; peroxisomal targeting signal 1 (SKL type) receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal 1 receptor; peroxisomal biogenesis factor 5; peroxisomal targeting signal import receptor; peroxisomal targeting signal receptor 1; peroxisome biogenesis factor 5; peroxisome receptor 1; PEX5; Pex5_predicted; PTS1 BP; PTS1 receptor; PTS1-BP; PTS1R; Pxr1; PXR1P; RCDP5; X83306
Gene Symbols Pex5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PEX5. Recombinant protein control fragment (Product #RP-102867).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5830
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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