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Tocris Bioscience™ PF 04418948

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Quantity:
10 mg
50 mg
Description
Potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 409.41 |
Purity | 98% |
Molecular Weight (g/mol) | 409.413 |
Chemical Name or Material | PF 04418948 |
Safety and Handling
Recommended Storage | Store at -20°C |
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