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  5. Tocris Bioscience™ PF 04449913 maleate

Tocris Bioscience™ PF 04449913 maleate
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Catalog No. 65385
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent Smo antagonist

PF 04449913 maleate is a potent Smo antagonist (IC50 = 5 nM). Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells.

Specifications

Chemical Name or Material 1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
CAS 2030410-25-2
Synonym glasdegib, PF-913
Quantity 5 mg
Molecular Formula C21H22N6O.C4H4O4
Purity 98%
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