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  5. Tocris Bioscience™ PF 04457845

Tocris Bioscience™ PF 04457845
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Catalog No. 63745
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Quantity:
5 mg
25 mg
Catalog No. Quantity
63-745 5 mg
63-742-5 25 mg
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Catalog No. 63-745

Supplier: Tocris Bioscience™ 6374/5

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Description

Potent and selective irreversible FAAH inhibitor

PF 04457845 is a potent and selective irreversible FAAH inhibitor (IC50 = 7.2 nM, which is selective for FAAH over a panel of other serine hydrolases. PF 04457845 exhibits efficacy in a rat inflammatory pain model, and is orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide
CAS 1020315-31-4
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C23H20F3N5O2
Formula Weight Observed MW: 455.43
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