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Tocris Bioscience™ PF 05175157

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Quantity:
10 mg
50 mg
Description
PF 05175157 is an potent acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively). Reduces hepatic and skeletal muscle malonyl-CoA levels in rats. Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats. Orally bioavailable.
Specifications
Specifications
Chemical Name or Material | 1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one |
CAS | 1301214-47-0 |
Quantity | 50 mg |
Target | Additional Lipid Metabolism Compounds |
Molecular Formula | C23H27N5O2 |
Formula Weight | 405.49 |
Purity | >98% |
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