Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ PF 4708671

Tocris Bioscience™ PF 4708671
GREENER_CHOICE

Catalog No. 403225
Change view
Click to view available options
Quantity:
5 mg
25 mg
Catalog No. Quantity
40-322-5 25 mg
40-325 5 mg
2 options
This item is not returnable. View return policy

Catalog No. 40-322-5

Supplier: Tocris Bioscience™ 4032/25

Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

S6K1 inhibitor

PF 4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) (Ki = 20 nM; IC50 = 160 nM). Suppresses the S6K1-mediated phosphorylation of S6, Rictor and mTOR in response to IGF1; displays no effect on the activity of RSK and MSK in vivo. Exhibits no significant inhibition of S6K2 or other AGC kinases (e.g. Akt, PKA and ROCK) in vitro.

Specifications

Chemical Name or Material 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole
CAS 1255517-76-0
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C19H21F3N6
Formula Weight Observed MW: 390.41
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.