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PF 573228, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
869288-64-2
C22H20F3N5O3S
491.489
HESLKTSGTIBHJU-UHFFFAOYSA-N
3,4-dihydro-6-4-3-methylsulfonyl phenyl methyl amino-5-trifluoromethyl-2-pyrimidinyl amino-2 1h-quinolinone,6-4-3-methylsulfonyl benzylamino-5-trifluoromethyl pyrimidin-2-ylamino-3,4-dihydroquinolin-2 1h-one,6-4-3-methanesulfonyl-benzylamino-5-trifluoromethyl-pyrimidin-2-ylamino-3,4-dihydro-1h-quinolin-2-one,3,4-dihydro-6-4-3-methylsulfonyl phenyl methyl amino-5-trifluoromethyl-pyrimidin-2-yl amino-2 1h-quinolinone,6-4-3-methanesulfonyl benzyl amino-5-trifluoromethylpyrimidin-2-yl amino-3,4-dihydro-1h-quinolin-2-one,6-4-3-methylsulfonyl benzyl amino-5-trifluoromethyl pyrimidin-2-yl amino-3,4-dihydroquinolin-2 1h-one,6-4-3-methanesulfonylphenyl methyl amino-5-trifluoromethyl pyrimidin-2-yl amino-3,4-dihydro-1h-quinolin-2-one,d02qaz,pf hplc
11612883
6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-quinolin-2-one
CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
This item is not returnable. View return policy
869288-64-2
C22H20F3N5O3S
491.489
HESLKTSGTIBHJU-UHFFFAOYSA-N
3,4-dihydro-6-4-3-methylsulfonyl phenyl methyl amino-5-trifluoromethyl-2-pyrimidinyl amino-2 1h-quinolinone,6-4-3-methylsulfonyl benzylamino-5-trifluoromethyl pyrimidin-2-ylamino-3,4-dihydroquinolin-2 1h-one,6-4-3-methanesulfonyl-benzylamino-5-trifluoromethyl-pyrimidin-2-ylamino-3,4-dihydro-1h-quinolin-2-one,3,4-dihydro-6-4-3-methylsulfonyl phenyl methyl amino-5-trifluoromethyl-pyrimidin-2-yl amino-2 1h-quinolinone,6-4-3-methanesulfonyl benzyl amino-5-trifluoromethylpyrimidin-2-yl amino-3,4-dihydro-1h-quinolin-2-one,6-4-3-methylsulfonyl benzyl amino-5-trifluoromethyl pyrimidin-2-yl amino-3,4-dihydroquinolin-2 1h-one,6-4-3-methanesulfonylphenyl methyl amino-5-trifluoromethyl pyrimidin-2-yl amino-3,4-dihydro-1h-quinolin-2-one,d02qaz,pf hplc
11612883
6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-quinolin-2-one
CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4

Potent and selective FAK inhibitor

Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.

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Quantity 10mg
Formula Weight 491.49
Percent Purity >98%
Chemical Name or Material PF 573228

Recommended Storage : Store at +4°C