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  5. Tocris Bioscience™ PF CBP1

Tocris Bioscience™ PF CBP1

Catalog No. 580110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective CBP/p300 bromodomain inhibitor

Selective CBP/p300 bromodomain inhibitor (IC50 values are 125 and 363 nM, respectively). Exhibits >100-fold selectivity for CBP over BRD4. Also exhibits selectivity over a panel of other bromodomains. Reduces LPS-induced IL-1β, IL-6 and IFN-β expression in macrophages in vitro. Also downregulates RGS4 expression in primary cortical neurons in vitro.

Negative Control also available.

Specifications

Chemical Name or Material 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole
CAS 1962928-21-7
Quantity 10 mg
Target Bromodomain Inhibitors
Molecular Formula C29H36N4O3
Formula Weight 488.62
Purity >98%
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